Wrists have a modified ball-and-socket joint. They are an important target of releases and come-a-longs. Although wrist locks are effective, they require years of practice to apply correctly. They must be learned to near perfection because they are so easily broken and countered, especially if the opponent is strong. Wrists may also be a target for strikes. A strike to a wrist may numb and paralyze the entire arm.
Fingers may be targets for either strikes or grabs where they are pulled painfully backward. A sharp strike to the fingers may make an opponent drop his or her weapon and may cripple the hand so it cannot be used it to continue an attack.
Should the situation be serious, or the assailant is under the influence of alcohol or drugs, targets on the legs become your primary targets. It is easy to damage the knee with a kick to the front or side. When the knee is damaged, whether your attacker is able to feel the pain or not, he or she will not be able to stand or follow you as you make your escape. A strike or kick to the muscles of the inner thigh will not only cause pain but may cause a cramp which would make the leg useless and bring your assailant down. A sharp strike to the unprotected shin bone or a stomp to the instep of the foot will be extremely painful and could easily hobble an assailant. A stomp to the Achilles tendon could possibly cripple an assailant. A kick to the calf could cause a painful cramp. A strike just above the knee and at the bottom of the thigh could tear the hamstring and cripple an assailant. These are all repairable injuries, but they will allow you opportunity to escape.