Predators rely on your fear to help them take you down. They circle, they howl, they rustle the bushes, they count on your fear causing you inaction. You must control and hide your fear so you do not appear as prey and, if the attack comes, you must channel your fear into a fierce counterattack.
Human predators have keener senses and instincts. You just left a well-lighted area, while they have been waiting in the shadows and are used to the darkness. They have been hidden for a while so they are aware of all the surrounding noises and how to use them to their benefit. You have trained your senses in a class environment; they have trained theirs where the attacks will take place, in the streets.
Human predators are strong where they need to be. While you may have honed your entire body into outstanding physical condition, they have only honed the parts they need to defeat you. They may be fat or out of shape, but any body part they need to defeat you will be tougher than any body part you use to defend against it.
You cannot talk to or soothe a charging wolf. Talking to a human predator or trying to negotiate a better outcome is usually a waste of time and only gives the predator a greater advantage. Trying to reason with an unreasonable person, one who is in a rage, or one who is under the influence of drugs is a waste of time. The time for talk is after you have eliminated the threat.